SOX9 GOVERNS DIFFERENTIATION STAGE-SPECIFIC GENE EXPRESSION IN GROWTH PLATE CHONDROCYTES VIA DIRECT CONCOMITANT TRANSACTIVATION AND REPRESSION.

SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression.

Cartilage and endochondral bone development require SOX9 activity to regulate chondrogenesis, chondrocyte proliferation, and transition to a non-mitotic hypertrophic state.The restricted and reciprocal expression of the collagen X gene, Col10a1, in hypertrophic chondrocytes and Sox9 in immature chondrocytes epitomise the precise spatiotemporal cont

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Racial discrimination & cardiovascular disease risk: my body my story study of 1005 US-born black and white community health center participants (US).

To date, limited and inconsistent evidence exists regarding racial discrimination and risk of cardiovascular disease (CVD).Cross-sectional observational study of 1005 US-born non-Hispanic black (n = 504) and white (n = 501) participants age 35-64 randomly selected from community health centers in Boston, MA (2008-2010; 82.4% response rate), Face us

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